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Research summaries, dosing protocols, and community reports for peptides. Built on clinical data and real-world experiences.
Aesthetic peptides target skin aging, hair loss, and cosmetic enhancement through mechanisms like collagen synthesis stimulation, neuromuscular modulation (Botox-like effects), and melanin production. Many are available in both injectable and topical formulations.
GHK-Cu leads this category with extensive research on wound healing, collagen synthesis, and gene expression modulation. Cosmetic peptides like Matrixyl and Argireline are widely used in skincare products, while Melanotan peptides affect pigmentation.
GHK-Cu (copper peptide) has the broadest evidence base for skin health. Research shows it stimulates collagen and glycosaminoglycan synthesis, promotes skin remodeling, and has antioxidant properties. It can be used both topically (in serums) and as subcutaneous injections.
Topical peptides like Matrixyl (palmitoyl pentapeptide-4) and Argireline (acetyl hexapeptide-3) have published clinical data showing modest improvements in wrinkle depth and skin texture. They work through different mechanisms — Matrixyl stimulates collagen, while Argireline inhibits neurotransmitter release similar to a mild topical Botox effect.
GHK-Cu has preliminary evidence for hair growth stimulation, potentially by increasing follicle size and promoting anagen phase. Some research suggests it may be comparable to minoxidil for certain types of hair loss. However, large-scale clinical trials for hair-specific indications are still needed.