SNAP-8 (Acetyl Octapeptide-3)

SNAP-8 is an octapeptide used in cosmetic applications to reduce wrinkles. Works by inhibiting neuromuscular signaling similar to botulinum toxin but through a different mechanism. Primarily used in topical formulations.

At a Glance

Summary: Inhibits SNARE complex formation to reduce neurotransmitter release at neuromuscular junctions, relaxing expression muscles and reducing wrinkles. Mechanisms (reported/proposed across domains): Skin / cosmetic • Mimics N-terminal of SNAP-25, competing with native protein in SNARE complex formation required for neurotransmitter release. • Reduces acetylcholine release at neuromuscular...

Safety Profile

Generally Well Tolerated (Topical)

Research Dosing

Dose: 3–10% in topical formulation · Route: Topical · Frequency: 1–2× daily (topical) · Duration: 4–8 weeks for visible results

Categories

  • Topical
  • Anti-Wrinkle
  • Cosmetic
  • Non-Invasive
  • Skin Health
  • SNARE Complex
  • Muscle Relaxation
  • Expression Lines
  • Peptide Serum
  • Well Tolerated

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