Melanotan II

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH) that activates melanocortin receptors. Studied for effects on skin pigmentation and sexual function.

At a Glance

Summary: Non-selectively activates multiple melanocortin receptors, stimulating melanin production, sexual arousal, and appetite suppression. Mechanisms (reported/proposed across domains): Skin / cosmetic • Activates MC1R receptors on melanocytes, stimulating eumelanin synthesis, producing skin darkening without UV exposure. Sexual function / libido • Activates MC3R/MC4R in central nervous...

Safety Profile

Investigational - Higher Risk Profile

Research Dosing

Dose: 0.25–1 mg · Route: Subcutaneous (SC) · Frequency: Daily (loading), then 1–2× weekly · Duration: 4–8 weeks max

Categories

  • Research Only
  • Tanning
  • Melanin Production
  • Sexual Function
  • Libido Enhancement
  • Appetite Suppression
  • Higher Risk
  • Preclinical Evidence
  • Not FDA Approved

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