Skin Health Peptides

Melanotan 1, also known as Afamelanotide, is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that selectively activates MC1R. Commonly administered via subcutaneous injection or nasal spray for tanning. FDA-approved as Scenesse (16 mg subcutaneous implant) for erythropoietic protoporphyria (EPP).

KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH). Research focuses on its potent anti-inflammatory properties, particularly in inflammatory bowel disease and skin conditions.

GHK-Cu is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Studied primarily for wound healing, skin regeneration, and anti-aging applications. Available in topical formulations.

GHK (Gly-His-Lys) is a naturally occurring tripeptide found in human plasma, saliva, and urine whose levels decline with age. Distinct from its copper-bound form (GHK-Cu), free GHK is researched for its ability to modulate gene expression patterns associated with tissue repair, anti-inflammation, and regeneration.

SNAP-8 is an octapeptide used in cosmetic applications to reduce wrinkles. Works by inhibiting neuromuscular signaling similar to botulinum toxin but through a different mechanism. Primarily used in topical formulations.

Matrixyl is a lipopeptide signal peptide used in cosmetic skincare to stimulate collagen production. It mimics the appearance of collagen breakdown fragments (matrikines), tricking skin cells into producing more collagen I, III, and IV. One of the most clinically validated anti-wrinkle peptides, found primarily in topical formulations.

Argireline is a synthetic hexapeptide widely used in cosmetic skincare as a topical alternative to botulinum toxin injections. It works by inhibiting the SNARE complex involved in neurotransmitter release, reducing the intensity of facial muscle contractions and softening expression lines — particularly around the eyes and forehead.