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GHK (Gly-His-Lys) is a naturally occurring tripeptide found in human plasma, saliva, and urine whose levels decline with age. Distinct from its copper-bound form (GHK-Cu), free GHK is researched for its ability to modulate gene expression patterns associated with tissue repair, anti-inflammation, and regeneration.
Summary: Resets gene expression patterns toward a healthier state by modulating over 4,000 genes, promoting tissue repair, reducing fibrosis, and activating stem cell-related pathways. Mechanisms (reported/proposed across domains): Gene expression / regeneration • Modulates expression of approximately 4,000 human genes, generally resetting expression patterns from a diseased/aged state toward a...
Generally Well Tolerated
Dose: 1–3 mg (injectable) or topical formulations · Route: Topical · Subcutaneous (SC) · Frequency: 1–2× daily · Duration: 4–12 weeks
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