The Leading Community for Trusted Peptide Research & Insights
Research summaries, dosing protocols, and community reports for peptides. Built on clinical data and real-world experiences.
MGF (Mechano Growth Factor) is a splice variant of the IGF-1 gene produced in response to mechanical loading of muscle tissue. Also known as IGF-1Ec in humans. Research focuses on muscle repair, satellite cell activation, and recovery from exercise-induced damage.
Summary: Activates satellite cells and promotes muscle repair through a unique E-domain peptide that is released during mechanical strain, working independently of the mature IGF-1 signaling pathway. Mechanisms (reported/proposed across domains): Muscle repair / recovery • The unique C-terminal E-domain peptide activates muscle satellite (stem) cells, initiating the repair response to...
Investigational - Very Limited Data
Dose: 200–400 mcg (PEG-MGF) · Route: Intramuscular (IM, site-specific) · Subcutaneous (SC) · Frequency: 2–3× weekly · Duration: 4–6 weeks (cycles)