Research Peptides Directory

Find detailed peptide profiles for Semaglutide, BPC-157, Tirzepatide, and more. Filter by category, development stage, or search by name.

Research Peptide Profiles

Development Stage
Regulatory Approval
Compounding Status

NAD+

Longevity & Cellular Health

NAD+ is a critical molecule for cellular energy production and repair that declines with age. Supplementing NAD+ precursors may help improve energy levels, brain function, and slow aspects of aging.

Epitalon (Epithalon)

Longevity & Cellular Health

Epitalon is an anti-aging peptide that may help slow cellular aging by activating telomerase, the enzyme that protects your DNA. It's one of the most studied longevity peptides.

MOTS-c

Longevity & Cellular Health

MOTS-c is a mitochondrial peptide that may boost metabolism and mimic some of the benefits of exercise. It's being studied for its potential to improve energy, blood sugar control, and fat burning.

SS-31 (Elamipretide)

Longevity & Cellular Health

SS-31 (Elamipretide) is a mitochondrial peptide that may protect and restore cellular energy production. It's being studied for age-related diseases, heart failure, and conditions caused by mitochondrial dysfunction.

Glutathione

Longevity & Cellular Health

Glutathione is the body's most abundant antioxidant, a small peptide that cells build themselves from three amino acids. It plays a key role in three things: protecting cells from damage by unstable molecules called free radicals, powering the mitochondria that make cellular energy, and helping the liver clear out drugs and toxins. Intracellular levels decline naturally with age, and low levels are linked to chronic illness, fatigue, and slower recovery from stress. People take it as a supplement by mouth (usually in a liposomal liquid for better absorption), through an IV at clinics, sprayed in the nose for brain-related research, or applied topically to the skin. Evidence supports real increases in measurable glutathione levels with supplementation, though the size of clinical effects varies by form, dose, and goal.

Humanin

Longevity & Cellular Health

Humanin is a naturally occurring mitochondrial peptide that may protect cells from stress and age-related damage. It's being studied for its potential role in Alzheimer's disease, diabetes, and cardiovascular health.

FOXO4-DRI

Longevity & Cellular Health

FOXO4-DRI is a peptide designed to selectively remove old, damaged cells (called senescent cells) that build up in the body with age. These cells stop dividing but refuse to die, releasing harmful signals that damage surrounding healthy tissue. FOXO4-DRI works by disrupting a specific protein interaction that keeps these cells alive, allowing them to undergo natural cell death. In animal studies, this led to improved fur growth, kidney function, and overall fitness in aged mice. No human clinical trials have been conducted, and the peptide remains a preclinical research compound.

About the Directory

How the Research Peptides Directory Works

The PeptideWiki directory organizes research peptides into clear, evidence-based profiles covering mechanisms, dosing, safety, and research status. Browse by category, development stage, or peptide name to compare compounds across weight loss, recovery, growth hormone, cognition, longevity, and more.

Categories

Peptides are grouped by their primary research focus and biological activity, including metabolism, growth hormone signaling, tissue repair, cognition, inflammation, aesthetics, cellular health, sexual health, and endocrine function.

Development Stage

Shows how far a peptide has progressed in the research pipeline. Preclinical compounds are still in laboratory or animal models. Phase 2, 3, and 4 compounds have moved further through human research. Discontinued compounds are no longer being actively developed.

Regulatory Approval

Shows whether a peptide has been cleared by a health authority or is still limited to research. "Not Approved" means no clinical clearance. "Investigational" means still under study. "FDA Approved" means cleared in the United States for specific indications.

Compounding Status

Shows where a peptide sits in the FDA 503A and 503B compounding pathways. Cat 1 compounds are under enforcement discretion and are compoundable today. Cat 2 compounds have safety concerns flagged. Withdrawn, Not Compoundable, and Component of FDA-Approved Drug categories each reflect different regulatory histories.