HGH Fragment 176-191

Metabolic & Weight Loss
Discontinued

HGH Fragment 176-191 is a stabilized piece of human growth hormone (amino acids 176-191) and the parent compound of AOD-9604. Research focuses on fat breakdown without the growth-promoting or blood sugar effects of full growth hormone.

Last updated February 22, 2026
2 PubMed-Verified Studies
Popular
Research-Driven Dosage Reports
RouteSubcutaneous (SC)
Dose250–500 mcg
Frequency1–2× daily
Duration8–12 weeks

Based on published research literature.

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Overview of HGH Fragment 176-191

Stimulates lipolysis and fat oxidation through a GH-receptor-independent mechanism, targeting adipose tissue without affecting IGF-1, glucose metabolism, or growth.

Metabolic / fat reduction

Mimics the lipolytic region of human growth hormone, stimulating hormone-sensitive lipase activity in adipose tissue.

Promotes fat oxidation and release of free fatty acids from adipocytes (proposed), particularly from stubborn visceral and abdominal fat stores.

Works independently of the GH receptor, meaning it does not elevate IGF-1 or promote tissue growth.

Metabolic safety

Does not affect blood glucose levels or insulin sensitivity (proposed), lacking the diabetogenic properties of full GH.

Does not promote longitudinal bone growth or organ hypertrophy, isolating the fat-metabolizing portion of GH.

Precursor to AOD-9604, which adds a tyrosine residue for improved stability but shares the same core mechanism

Read Full HGH Fragment 176-191 Dosage Guide

Research-backed dosing protocols, timing, and administration details

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Metabolic & Weight Loss