Thymalin

Immune & Inflammation
Preclinical
Russia Approved

Thymalin is a peptide complex originally extracted from calf thymus glands, developed in Russia. Research focuses on immune system restoration, anti-aging effects, and recovery of thymus gland function, particularly in elderly and immune-compromised individuals.

Last updated February 22, 2026
196 PubMed-Verified Studies
Moderate
Research-Driven Dosage Reports
RouteIntramuscular (IM)
Dose5–10 mg
Frequency1× daily for 5–10 days
Duration5–10 day courses, repeated every 3–6 months

Based on published research literature.

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Overview of Thymalin

Restores thymic function and T-cell differentiation, normalizing immune balance and neuroendocrine regulation in aging and immunodeficiency.

Immune restoration

Promotes maturation and differentiation of T-lymphocytes from thymic precursors, restoring cellular immunity.

Normalizes CD4/CD8 T-cell ratios (proposed), which decline with age-related thymic involution.

Stimulates phagocytic activity of neutrophils and macrophages, enhancing innate immune surveillance.

Aging / neuroendocrine

May partially reverse age-related thymic involution (proposed), restoring thymic hormone production.

Influences neuroendocrine regulation, with reported effects on melatonin and cortisol rhythms in elderly subjects.

Associated with reduced mortality in long-term studies of elderly populations in Russia (proposed)

Read Full Thymalin Dosage Guide

Research-backed dosing protocols, timing, and administration details

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Immune & Inflammation