Immune Modulation Peptides
Modulates immune system responses
Immunomodulatory peptides regulate and balance immune responses rather than simply boosting or suppressing them. This distinction is critical: in autoimmune conditions, the immune system is overactive against the body's own tissues, so stimulating it further would be counterproductive. Immunomodulators help recalibrate the immune system toward appropriate responses, enhancing defense against real threats while reducing misdirected attacks.
Key compounds include thymosin alpha-1 (restores T-cell function and is used clinically for hepatitis B and as a cancer immunotherapy adjunct), KPV (a tripeptide that reduces excessive inflammation through alpha-MSH pathways), and BPC-157 (which modulates multiple inflammatory pathways). These peptides are relevant for chronic infection, immune imbalance, post-illness recovery, and conditions involving dysregulated immunity.
This page collects every peptide on PeptideWiki tagged for immune modulation. Browse individual profiles for mechanisms, dosing, and safety data.
Peptides (5)
VIP (Vasoactive Intestinal Peptide)
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid brain and gut signaling peptide with wide-ranging effects on the immune and nervous systems. Research explores its anti-inflammatory properties and potential in autoimmune and neurodegenerative conditions.
Thymosin Alpha-1
Thymosin Alpha-1 is a 28-amino-acid peptide naturally produced by the thymus gland. It has been extensively studied for immune support with over 70 clinical trials. Research covers hepatitis treatment, cancer immune therapy, and sepsis management.
LL-37 (Cathelicidin)
LL-37 is a natural human immune defense molecule (part of the cathelicidin family) that plays a key role in the body's first line of defense against infection. Research explores its antimicrobial, wound healing, and immune-regulating properties.
KPV
KPV is a naturally occurring three-amino-acid peptide derived from alpha-MSH, a hormone involved in inflammation control. Research focuses on its strong anti-inflammatory properties, particularly in inflammatory bowel disease and skin conditions.
Thymalin
Thymalin is a peptide complex originally extracted from calf thymus glands, developed in Russia. Research focuses on immune system restoration, anti-aging effects, and recovery of thymus gland function, particularly in elderly and immune-compromised individuals.