Best Peptides for Hormone Optimization
Peptides that modulate the endocrine system beyond the growth hormone axis
Endocrine peptides beyond the GH axis play crucial roles in hormonal regulation — from gonadal function to adrenal health to thyroid signaling. These compounds are increasingly relevant in the context of hormone replacement therapy (HRT) and fertility treatments.
Gonadorelin, for example, is commonly used alongside testosterone therapy to maintain natural LH/FSH production and preserve fertility. ACTH (Cosyntropin) serves primarily as a diagnostic tool for adrenal function but has therapeutic applications as well.
Hormone Optimization Peptides (4)
Oxytocin
Oxytocin is a naturally occurring nine-amino-acid hormone produced in the brain, often called the "love hormone" for its role in social bonding and trust. It is FDA-approved for inducing labor and controlling postpartum bleeding, and is also being studied for autism, anxiety, and social disorders.
Kisspeptin-10
Kisspeptin is a brain signaling peptide that plays a critical role in reproductive hormone regulation. It works upstream of GnRH to control the hormone signaling chain between the brain and reproductive organs. It is being studied for fertility and puberty disorders.
Gonadorelin (GnRH)
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a key reproductive signaling hormone. It is used diagnostically and therapeutically for fertility assessment, low hormone levels, and to maintain testicular function during testosterone replacement therapy.
ACTH (Cosyntropin)
Cosyntropin is a synthetic version of the first 24 building blocks of the body's natural stress hormone ACTH. It is used as an FDA-approved diagnostic tool (Cortrosyn) to test whether the adrenal glands are working properly, and is also used to treat certain conditions like infantile spasms.