5-Amino-1MQ
5-Amino-1MQ is a small molecule that blocks an enzyme linked to fat storage and metabolic problems. Research focuses on fat cell metabolism, weight loss, and reversing diet-related obesity in animal studies.
A leading innovator in research chemicals.
|Exclusive OfferUse our affiliate link and code PEPTIDEWIKI at checkout to unlock your 10% discount, every time you use the code.
Shop NowFor research purposes only. PeptideWiki may earn a commission at no extra cost to you.
5-Amino-1MQ
For research purposes only. PeptideWiki may earn a commission at no extra cost to you.
Overview of 5-Amino-1MQ
Inhibits NNMT enzyme activity in adipose tissue, increasing cellular NAD+ and SAM levels to promote fat cell energy expenditure and shrink adipocytes.
Selectively inhibits NNMT, preventing methylation and degradation of nicotinamide, thereby increasing intracellular NAD+ levels in adipocytes.
Elevated NAD+ activates sirtuin-dependent metabolic pathways (proposed), increasing fat cell energy expenditure and reducing lipid storage.
Increases S-adenosylmethionine (SAM) availability by reducing NNMT-mediated SAM consumption, supporting methylation reactions.
Reverses diet-induced obesity in mouse models without changes in food intake or exercise, shrinking adipocyte size.
Reduces total cholesterol levels (proposed), improving lipid profiles in preclinical studies.
Does not cross the blood-brain barrier (proposed), minimizing CNS side effects while targeting peripheral fat metabolism
Read Full 5-Amino-1MQ Dosage Guide
Research-backed dosing protocols, timing, and administration details
Browse more in this category
Metabolic & Weight Loss
