Pinealon

Cognition, Mood & Neuroprotection
Preclinical
Russia Approved

Pinealon is a synthetic three-amino-acid peptide that may help regulate pineal gland and central nervous system function. Developed in Russia, research focuses on sleep regulation, brain cell protection, and cognitive function in aging.

Last updated February 22, 2026
31 PubMed-Verified Studies
Niche
Research-Driven Dosage Reports
RouteOral (sublingual) · Intranasal
Dose5–10 mg (sublingual capsules)
Frequency1× daily (PM)
Duration10–30 day courses

Based on published research literature.

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Overview of Pinealon

Acts as a peptide bioregulator targeting pineal gland and CNS gene expression to normalize melatonin production, sleep architecture, and neuroprotective pathways.

Sleep / circadian

Normalizes melatonin synthesis in the pineal gland (proposed), restoring circadian rhythm regulation that declines with age.

Improves sleep architecture and reduces sleep latency (proposed), particularly in elderly subjects with disrupted sleep patterns.

Neuro / cognition

Modulates expression of genes involved in neuronal survival and neurotransmitter metabolism in brain tissue (proposed).

Demonstrates neuroprotective activity against oxidative stress and excitotoxicity in cell culture models.

Penetrates the blood-brain barrier due to small size (proposed), enabling direct CNS effects.

Aging / neuroendocrine

Proposed to normalize age-related decline in pineal function, which correlates with immune and metabolic deterioration

Read Full Pinealon Dosage Guide

Research-backed dosing protocols, timing, and administration details

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Cognition, Mood & Neuroprotection