DSIP (Delta Sleep Inducing Peptide)

DSIP is a naturally occurring neuropeptide first isolated from rabbit brain tissue. Research focuses on sleep induction, stress reduction, and neuroendocrine modulation. Shows complex, context-dependent effects.

At a Glance

Summary: Proposed to modulate GABA, somatostatin, and circadian systems to promote deep sleep and reduce stress responses. Mechanisms (reported/proposed across domains): Sleep / circadian • Proposed to promote delta (slow-wave) sleep, the deepest and most restorative sleep phase. • Effects appear context-dependent, which may normalize rather than simply induce sleep. • Proposed effects on...

Safety Profile

Investigational - Limited Data

Research Dosing

Dose: 100–300 mcg · Route: Subcutaneous (SC) · Intranasal · Frequency: 1× before bed · Duration: 2–4 weeks

Categories

  • Research Only
  • Sleep
  • Deep Sleep
  • Stress Reduction
  • Cortisol Modulation
  • Circadian Rhythm
  • Pain Modulation
  • Neuropeptide
  • Limited Evidence
  • Not FDA Approved

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