Cerebrolysin

Cognition, Mood & Neuroprotection
Phase 4
Russia Approved

Cerebrolysin is a preparation derived from pig brain tissue containing small brain-protective peptides and amino acids. It is approved in many countries (but not the United States) for stroke, traumatic brain injury, and dementia. It is one of the most extensively studied brain peptide formulations.

Last updated March 6, 2026
301 PubMed-Verified Studies
Popular
Research-Driven Dosage Reports
RouteIntravenous (IV) · Intramuscular (IM)
Dose10–30 ml IV (daily in clinical trials)
Frequency1× daily
Duration10–20 days per course

Based on published research literature.

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Overview of Cerebrolysin

Provides neurotrophic factor-like activity through a mixture of brain-derived peptides, supporting neuronal survival, synaptic plasticity, and neurogenesis.

Neuro / cognition

Contains peptides with activity resembling BDNF, GDNF, NGF, and CNTF, supporting neuronal survival and differentiation.

Enhances synaptic plasticity and long-term potentiation (proposed), which may improve learning and memory formation.

Stimulates neurogenesis in the hippocampus (proposed), potentially relevant to recovery from brain injury.

Neuroprotection

Reduces excitotoxic damage by modulating calcium influx and glutamate signaling in neurons under stress.

Inhibits calpain-mediated cytoskeletal breakdown (proposed), preserving neuronal structural integrity after injury.

Reduces amyloid-beta pathology and tau phosphorylation in preclinical Alzheimer's models (proposed).

Stroke / TBI recovery

Improves functional outcomes in acute ischemic stroke trials, with benefits in motor and cognitive recovery.

May reduce infarct volume and promote perilesional neuroplasticity (proposed), supporting post-stroke rehabilitation

Read Full Cerebrolysin Dosage Guide

Research-backed dosing protocols, timing, and administration details

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Cognition, Mood & Neuroprotection