Dihexa

Cognition, Mood & Neuroprotection
Phase 2
Investigational

Dihexa is a synthetic six-amino-acid peptide related to angiotensin IV with strong cognitive-enhancing properties. It has been proposed to be millions of times more potent than natural brain growth factors at promoting nerve cell connections. Research focuses on cognitive enhancement and neurodegenerative diseases.

Last updated February 22, 2026
18 PubMed-Verified Studies
Popular
Research-Driven Dosage Reports
RouteIntranasal · Subcutaneous (SC)
Dose10–20 mg (oral) or 1–5 mg (injectable)
Frequency1× daily
Duration2–4 weeks

Based on published research literature.

Swiss Chems|Exclusive Offer
Coupon
10%
Off

Use our affiliate link and code PEPTIDEWIKI at checkout to unlock your 10% discount, every time you use the code.

Shop Now

For research purposes only. PeptideWiki may earn a commission at no extra cost to you.

Overview of Dihexa

Activates HGF signaling through c-Met receptor to promote synaptogenesis, enhance memory, and support neuronal survival.

Neuro / cognition

Binds to and activates c-Met (hepatocyte growth factor receptor), triggering downstream signaling cascades.

Mimics effects of hepatocyte growth factor, a potent neurotrophic factor involved in neuronal development and repair.

Promotes formation of new synaptic connections (proposed), potentially enhancing learning and memory formation.

Shows memory enhancement in animal models of cognitive impairment, proposed for Alzheimer's research.

Oral bioavailability

Unlike many peptides, shows oral activity, though injectable forms also used

Read Full Dihexa Dosage Guide

Research-backed dosing protocols, timing, and administration details

Browse more in this category

Cognition, Mood & Neuroprotection