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Dihexa is a synthetic hexapeptide analog of angiotensin IV with potent nootropic properties. Proposed to be 10 million times more potent than BDNF at promoting synaptic connectivity. Investigated for cognitive enhancement and neurodegenerative diseases.
Summary: Activates HGF signaling through c-Met receptor to promote synaptogenesis, enhance memory, and support neuronal survival. Mechanisms (reported/proposed across domains): Neuro / cognition • Binds to and activates c-Met (hepatocyte growth factor receptor), triggering downstream signaling cascades. • Mimics effects of hepatocyte growth factor, a potent neurotrophic factor involved in...
Investigational - Very Limited Data
Dose: 10–20 mg (oral) or 1–5 mg (injectable) · Route: Intranasal · Subcutaneous (SC) · Frequency: 1× daily · Duration: 2–4 weeks