Selank

Cognition, Mood & Neuroprotection
Preclinical
Russia Approved

Selank is a synthetic seven-amino-acid peptide derived from the immune protein tuftsin, developed in Russia. Research shows it has both immune-supporting and anti-anxiety properties without causing sedation or dependence.

Last updated February 22, 2026
140 PubMed-Verified Studies
Very Popular
Research-Driven Dosage Reports
RouteIntranasal · Subcutaneous (SC)
Dose200–400 mcg
Frequency2–3× daily (intranasal)
Duration2–4 weeks

Based on published research literature.

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Overview of Selank

Modulates GABA-A receptors and enhances enkephalin activity to reduce anxiety, while regulating cytokines for immunomodulatory effects.

Neuro / anxiety

Enhances GABAergic neurotransmission, producing anxiolytic effects comparable to benzodiazepines without sedation or dependence.

Inhibits enkephalinase enzymes, increasing endogenous enkephalin levels and modulating opioid system for stress relief.

No tolerance, dependence, or cognitive impairment unlike benzodiazepines, with a favorable safety profile.

Inflammation / immune

Modulates pro- and anti-inflammatory cytokines (suppresses IL-6, TNF-α), providing immunomodulatory effects alongside anxiolytic properties.

Affects expression of genes involved in GABAergic neurotransmission, which may induce interferon secretion for antiviral activity

Read Full Selank Dosage Guide

Research-backed dosing protocols, timing, and administration details

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