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Selank is a synthetic heptapeptide analog of tuftsin developed in Russia as an anxiolytic and nootropic. Shows both immunomodulatory and anxiolytic properties without sedation or dependence in research studies.
Summary: Modulates GABA-A receptors and enhances enkephalin activity to reduce anxiety, while regulating cytokines for immunomodulatory effects. Mechanisms (reported/proposed across domains): Neuro / anxiety • Enhances GABAergic neurotransmission, producing anxiolytic effects comparable to benzodiazepines without sedation or dependence. • Inhibits enkephalinase enzymes, increasing endogenous...
Approved in Russia - Not FDA Approved
Dose: 200–400 mcg · Route: Intranasal · Subcutaneous (SC) · Frequency: 2–3× daily (intranasal) · Duration: 2–4 weeks