The Leading Community for Trusted Peptide Research & Insights
Research summaries, dosing protocols, and community reports for peptides. Built on clinical data and real-world experiences.
Semax is a synthetic heptapeptide derived from ACTH(4-10) fragment, developed in Russia for neuroprotective and cognitive-enhancing applications. Research focuses on stroke recovery, cognitive function, and BDNF modulation.
Summary: Rapidly upregulates BDNF and TrkB receptor expression, modulates neurotransmission genes, and influences serotonergic and dopaminergic pathways. Mechanisms (reported/proposed across domains): Neuro / cognition • Rapidly increases Brain-Derived Neurotrophic Factor and TrkB receptor expression in hippocampus, enhancing neuroplasticity and memory. • Affects over 1,500 genes in stroke...
Approved in Russia - Not FDA Approved
Dose: 200–600 mcg · Route: Intranasal · Subcutaneous (SC) · Frequency: 1–3× daily (intranasal) · Duration: 2–8 weeks