BDNF Enhancement Peptides

Semax is a synthetic heptapeptide derived from ACTH(4-10) fragment, developed in Russia for neuroprotective and cognitive-enhancing applications. Research focuses on stroke recovery, cognitive function, and BDNF modulation.

Cerebrolysin is a porcine brain-derived peptide preparation containing low-molecular-weight neuropeptides and free amino acids. Approved in many countries (not the US) for stroke, traumatic brain injury, and dementia. One of the most studied neuropeptide formulations.

Dihexa is a synthetic hexapeptide analog of angiotensin IV with potent nootropic properties. Proposed to be 10 million times more potent than BDNF at promoting synaptic connectivity. Investigated for cognitive enhancement and neurodegenerative diseases.

PE-22-28 is a synthetic 7-amino-acid peptide derived from the spadin family, designed to inhibit the TREK-1 potassium channel. Research focuses on antidepressant-like effects and cognitive enhancement through BDNF-mediated neuroplasticity in preclinical models.