Melanocortin Peptides

PT-141 (Bremelanotide) is a melanocortin receptor agonist studied for sexual dysfunction. Works centrally in the brain rather than peripherally like PDE-5 inhibitors. Marketed as Vyleesi for premenopausal women with HSDD.

KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH). Research focuses on its potent anti-inflammatory properties, particularly in inflammatory bowel disease and skin conditions.

Cosyntropin is a synthetic analog of the first 24 amino acids of adrenocorticotropic hormone (ACTH 1-24). It is FDA-approved as a diagnostic agent for adrenal insufficiency testing (Cortrosyn). Also used therapeutically in certain conditions such as infantile spasms.