GHRP Peptides
Growth hormone releasing peptide
GHRPs (growth hormone releasing peptides) are a family of synthetic peptides that stimulate the pituitary gland to release growth hormone by activating the ghrelin receptor (GHS-R1a). The family includes GHRP-2, GHRP-6, hexarelin, and ipamorelin, each with slightly different receptor selectivity and side effect profiles. They are typically combined with GHRH analogs (like CJC-1295) for synergistic GH release.
The key distinction between GHRPs is their selectivity. Ipamorelin is the most selective, producing GH release with minimal effects on cortisol, prolactin, or appetite. GHRP-6 is the least selective, also stimulating appetite and raising cortisol and prolactin. GHRP-2 falls in between. Hexarelin produces the strongest GH release but also the most cortisol and prolactin elevation. Choosing the right GHRP depends on which side effects are acceptable for your goals.
This page collects every GHRP on PeptideWiki. Browse individual profiles for specific receptor profiles, dosing, and safety data.
Peptides (4)
MK-677 (Ibutamoren)
MK-677 (Ibutamoren) is an oral (non-injectable) compound that triggers growth hormone release by mimicking the hunger hormone ghrelin. Research focuses on increasing growth hormone and IGF-1 levels, improving sleep quality, body composition, and bone density.
GHRP-6
GHRP-6 (Growth Hormone Releasing Peptide-6) is a six-amino-acid peptide that triggers growth hormone release through the ghrelin (hunger hormone) receptor. It is known for strong growth hormone release but also significant appetite stimulation.
Hexarelin
Hexarelin is a synthetic six-amino-acid peptide and one of the most potent compounds that trigger growth hormone release. Beyond its growth hormone effects, research also shows heart-protective properties that work independently of growth hormone.
GHRP-2
GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic six-amino-acid peptide that triggers growth hormone release. It is considered more potent than GHRP-6 with less appetite stimulation.