Best Peptides for Immune Support

Immune peptides encompass both immunostimulatory compounds (like Thymosin Alpha-1) and anti-inflammatory peptides (like KPV). They work through diverse mechanisms — from thymic hormone modulation to antimicrobial activity to cytokine regulation.

Thymosin Alpha-1 stands out with the strongest clinical evidence, having been approved in over 30 countries for hepatitis and as an immune adjuvant. Other peptides in this category are at earlier stages of research but show promising immunomodulatory properties.

Peptides for Immune Support Peptides

  • ARA-290 (Cibinetide) — ARA-290 (cibinetide) is a synthetic 11-amino-acid peptide derived from the non-erythropoietic, tissue-protective domain...
  • KPV — KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating...
  • LL-37 (Cathelicidin) — LL-37 is an endogenous human antimicrobial peptide (cathelicidin) that plays a role in innate immunity. Research...
  • Thymalin — Thymalin is a polypeptide complex originally extracted from calf thymus glands, developed in Russia. Research focuses...
  • Thymosin Alpha-1 — Thymosin Alpha-1 (Tα1) is a 28 amino acid peptide naturally produced by the thymus gland. Extensively studied for...
  • VIP (Vasoactive Intestinal Peptide) — VIP (Vasoactive Intestinal Peptide) is a 28 amino acid neuropeptide with complex neuroendocrine and immunomodulatory...

Frequently Asked Questions

What is the best peptide for immune function?

Thymosin Alpha-1 has the strongest clinical evidence for immune support, with FDA orphan drug status and approval in 30+ countries. It enhances T-cell function, dendritic cell maturation, and has been studied as an adjunct in cancer immunotherapy and chronic infections.

What is KPV peptide used for?

KPV is a tripeptide (Lys-Pro-Val) derived from alpha-MSH with potent anti-inflammatory properties. It has been studied for inflammatory bowel conditions, skin inflammation, and general immune modulation. It can be administered orally, subcutaneously, or topically.

Is LL-37 an antibiotic peptide?

LL-37 is an antimicrobial peptide (AMP) naturally produced by the human immune system. It has direct antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects. It's being researched as a potential alternative or adjunct to conventional antibiotics.

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