Best Peptides for Immune Support
Immunomodulatory and anti-inflammatory peptides studied for immune system optimization
Immune peptides encompass both immunostimulatory compounds (like Thymosin Alpha-1) and anti-inflammatory peptides (like KPV). They work through diverse mechanisms — from thymic hormone modulation to antimicrobial activity to cytokine regulation.
Thymosin Alpha-1 stands out with the strongest clinical evidence, having been approved in over 30 countries for hepatitis and as an immune adjuvant. Other peptides in this category are at earlier stages of research but show promising immunomodulatory properties.
Immune Support Peptides (6)
VIP (Vasoactive Intestinal Peptide)
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid brain and gut signaling peptide with wide-ranging effects on the immune and nervous systems. Research explores its anti-inflammatory properties and potential in autoimmune and neurodegenerative conditions.
Thymosin Alpha-1
Thymosin Alpha-1 is a 28-amino-acid peptide naturally produced by the thymus gland. It has been extensively studied for immune support with over 70 clinical trials. Research covers hepatitis treatment, cancer immune therapy, and sepsis management.
LL-37 (Cathelicidin)
LL-37 is a natural human immune defense molecule (part of the cathelicidin family) that plays a key role in the body's first line of defense against infection. Research explores its antimicrobial, wound healing, and immune-regulating properties.
ARA-290 (Cibinetide)
ARA-290 (cibinetide) is a synthetic 11-amino-acid peptide based on the tissue-protective part of erythropoietin, without stimulating red blood cell production. Research focuses on nerve pain, small fiber neuropathy, sarcoidosis, and metabolic syndrome.
KPV
KPV is a naturally occurring three-amino-acid peptide derived from alpha-MSH, a hormone involved in inflammation control. Research focuses on its strong anti-inflammatory properties, particularly in inflammatory bowel disease and skin conditions.
Thymalin
Thymalin is a peptide complex originally extracted from calf thymus glands, developed in Russia. Research focuses on immune system restoration, anti-aging effects, and recovery of thymus gland function, particularly in elderly and immune-compromised individuals.