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Ipamorelin is a selective growth hormone secretagogue developed by Novo Nordisk. It stimulates GH release without significantly affecting cortisol or prolactin levels. Has been studied in clinical trials for postoperative recovery.
Summary: Selectively activates ghrelin receptors to stimulate growth hormone release without significantly affecting cortisol or prolactin levels. Mechanisms (reported/proposed across domains): Growth hormone axis • Selectively binds and activates ghrelin receptor (GHS-R1a) in the pituitary, triggering GH release with high selectivity. • Produces dose-proportional increase in circulating GH...
Investigational - Development Discontinued
Dose: 100–300 mcg · Route: Subcutaneous (SC) · Frequency: 1–3× daily · Duration: 8–12 weeks
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