MK-677 (Ibutamoren)

Growth Hormone / IGF-1 Axis

MK-677 (Ibutamoren) is an orally active, non-peptide growth hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. Research focuses on increasing GH and IGF-1 levels, improving sleep quality, body composition, and bone density.

Very Popular

IGF-1 LR3

Growth Hormone / IGF-1 Axis

IGF-1 LR3 (Long R3 IGF-1) is a modified analog of insulin-like growth factor 1 with an arginine substitution at position 3 and a 13-amino-acid extension. These modifications reduce IGF binding protein affinity, increasing potency and half-life compared to native IGF-1.

Very Popular

CJC-1295 (Modified GRF 1-29)

Growth Hormone / IGF-1 Axis

CJC-1295 is a synthetic GHRH (Growth Hormone-Releasing Hormone) analog with extended duration due to Drug Affinity Complex technology. Studied for its effects on growth hormone release and body composition.

Very Popular

CJC-1295 with DAC

Growth Hormone / IGF-1 Axis

CJC-1295 with DAC (Drug Affinity Complex) is a long-acting GHRH analog that uses a maleimidopropionic acid linker to bind serum albumin, extending its half-life to several days. This provides sustained GH elevation compared to the shorter-acting Mod GRF 1-29 (CJC-1295 without DAC).

Very Popular

Sermorelin

Growth Hormone / IGF-1 Axis

Sermorelin is a synthetic 29-amino acid analog of growth hormone-releasing hormone (GHRH). It was FDA-approved for pediatric growth hormone deficiency and is widely used off-label for anti-aging and body composition optimization.

Very Popular

Ipamorelin

Growth Hormone / IGF-1 Axis

Ipamorelin is a selective growth hormone secretagogue developed by Novo Nordisk. It stimulates GH release without significantly affecting cortisol or prolactin levels. Has been studied in clinical trials for postoperative recovery.

Very Popular

GHRP-6

Growth Hormone / IGF-1 Axis

GHRP-6 (Growth Hormone Releasing Peptide-6) is a hexapeptide that stimulates growth hormone release through the ghrelin receptor. Known for potent GH release but also significant appetite stimulation.

Popular

Hexarelin

Growth Hormone / IGF-1 Axis

Hexarelin is a synthetic hexapeptide growth hormone secretagogue, considered one of the most potent GHRPs available. Also shows cardioprotective properties independent of GH release.

Moderate

GHRP-2

Growth Hormone / IGF-1 Axis

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide that stimulates growth hormone secretion. Considered more potent than GHRP-6 with less appetite stimulation.

Niche