Peptide Directory

Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme found in every living cell. It is essential for mitochondrial function, DNA repair, and cellular energy metabolism. Levels decline with age, and supplementation is researched for anti-aging and metabolic health.

Body Protection Compound-157 (BPC-157) is a 15-amino-acid fragment originally isolated from proteins in the human stomach lining. Most evidence comes from animal studies exploring wound healing, tendon repair, and gut health applications.

Semax is a synthetic heptapeptide derived from ACTH(4-10) fragment, developed in Russia for neuroprotective and cognitive-enhancing applications. Research focuses on stroke recovery, cognitive function, and BDNF modulation.

MK-677 (Ibutamoren) is an orally active, non-peptide growth hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. Research focuses on increasing GH and IGF-1 levels, improving sleep quality, body composition, and bone density.

CJC-1295 with DAC (Drug Affinity Complex) is a long-acting GHRH analog that uses a maleimidopropionic acid linker to bind serum albumin, extending its half-life to several days. This provides sustained GH elevation compared to the shorter-acting Mod GRF 1-29 (CJC-1295 without DAC).

IGF-1 LR3 (Long R3 IGF-1) is a modified analog of insulin-like growth factor 1 with an arginine substitution at position 3 and a 13-amino-acid extension. These modifications reduce IGF binding protein affinity, increasing potency and half-life compared to native IGF-1.

CJC-1295 is a synthetic GHRH (Growth Hormone-Releasing Hormone) analog with extended duration due to Drug Affinity Complex technology. Studied for its effects on growth hormone release and body composition.

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH) that activates melanocortin receptors. Studied for effects on skin pigmentation and sexual function.

Sermorelin is a synthetic 29-amino acid analog of growth hormone-releasing hormone (GHRH). It was FDA-approved for pediatric growth hormone deficiency and is widely used off-label for anti-aging and body composition optimization.

Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied primarily in Russia. Research focuses on telomerase activation, pineal gland function, and potential anti-aging mechanisms.

Ipamorelin is a selective growth hormone secretagogue developed by Novo Nordisk. It stimulates GH release without significantly affecting cortisol or prolactin levels. Has been studied in clinical trials for postoperative recovery.

Selank is a synthetic heptapeptide analog of tuftsin developed in Russia as an anxiolytic and nootropic. Shows both immunomodulatory and anxiolytic properties without sedation or dependence in research studies.

Cerebrolysin is a porcine brain-derived peptide preparation containing low-molecular-weight neuropeptides and free amino acids. Approved in many countries (not the US) for stroke, traumatic brain injury, and dementia. One of the most studied neuropeptide formulations.

MOTS-c is a 16 amino acid mitochondrial-derived peptide encoded in the 12S rRNA gene. First mitochondrial peptide to enter clinical trials. Emerging evidence for metabolic health, exercise performance, and longevity. Levels decline with age.

GHRP-6 (Growth Hormone Releasing Peptide-6) is a hexapeptide that stimulates growth hormone release through the ghrelin receptor. Known for potent GH release but also significant appetite stimulation.

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4, a naturally occurring protein involved in tissue repair. Research focuses on wound healing, tissue regeneration, and reducing inflammation.

VIP (Vasoactive Intestinal Peptide) is a 28 amino acid neuropeptide with complex neuroendocrine and immunomodulatory functions. Research explores its anti-inflammatory properties and potential in autoimmune and neurodegenerative conditions.

DSIP is a naturally occurring neuropeptide first isolated from rabbit brain tissue. Research focuses on sleep induction, stress reduction, and neuroendocrine modulation. Shows complex, context-dependent effects.

Follistatin is a naturally occurring glycoprotein that binds and inhibits myostatin, a negative regulator of muscle growth. Studied for muscle wasting conditions and performance enhancement. Gene therapy approaches also in development.

LL-37 is an endogenous human antimicrobial peptide (cathelicidin) that plays a role in innate immunity. Research explores its antimicrobial, wound healing, and immunomodulatory properties.

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH). Used diagnostically and therapeutically for fertility, hypogonadism, and to maintain testicular function during testosterone replacement therapy.

Humanin is a 24-amino-acid mitochondrial-derived peptide encoded in the 16S rRNA gene. Discovered for its ability to protect neurons from amyloid-beta toxicity. Research explores its roles in neuroprotection, metabolic regulation, and cellular stress resistance.

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to obesity and metabolic dysfunction. Research focuses on fat cell metabolism, weight loss, and reversing diet-induced obesity in preclinical models.

MGF (Mechano Growth Factor) is a splice variant of the IGF-1 gene produced in response to mechanical loading of muscle tissue. Also known as IGF-1Ec in humans. Research focuses on muscle repair, satellite cell activation, and recovery from exercise-induced damage.

HGH Fragment 176-191 is a stabilized fragment of the C-terminal portion of human growth hormone (amino acids 176-191). It is the parent compound of AOD-9604. Research focuses on fat metabolism and lipolysis without the growth-promoting or diabetogenic effects of full GH.

KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH). Research focuses on its potent anti-inflammatory properties, particularly in inflammatory bowel disease and skin conditions.

GHK (Gly-His-Lys) is a naturally occurring tripeptide found in human plasma, saliva, and urine whose levels decline with age. Distinct from its copper-bound form (GHK-Cu), free GHK is researched for its ability to modulate gene expression patterns associated with tissue repair, anti-inflammation, and regeneration.

GHK-Cu is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Studied primarily for wound healing, skin regeneration, and anti-aging applications. Available in topical formulations.

AOD-9604 is a modified C-terminal fragment of human growth hormone (amino acids 176-191). Originally developed as an anti-obesity agent. Shows preclinical evidence for promoting fat metabolism without affecting blood sugar or growth.

SNAP-8 is an octapeptide used in cosmetic applications to reduce wrinkles. Works by inhibiting neuromuscular signaling similar to botulinum toxin but through a different mechanism. Primarily used in topical formulations.

Hexarelin is a synthetic hexapeptide growth hormone secretagogue, considered one of the most potent GHRPs available. Also shows cardioprotective properties independent of GH release.

Matrixyl is a lipopeptide signal peptide used in cosmetic skincare to stimulate collagen production. It mimics the appearance of collagen breakdown fragments (matrikines), tricking skin cells into producing more collagen I, III, and IV. One of the most clinically validated anti-wrinkle peptides, found primarily in topical formulations.

Argireline is a synthetic hexapeptide widely used in cosmetic skincare as a topical alternative to botulinum toxin injections. It works by inhibiting the SNARE complex involved in neurotransmitter release, reducing the intensity of facial muscle contractions and softening expression lines — particularly around the eyes and forehead.

Thymalin is a polypeptide complex originally extracted from calf thymus glands, developed in Russia. Research focuses on immune restoration, anti-aging effects, and thymic function recovery, particularly in elderly and immunocompromised subjects.

PE-22-28 is a synthetic 7-amino-acid peptide derived from the spadin family, designed to inhibit the TREK-1 potassium channel. Research focuses on antidepressant-like effects and cognitive enhancement through BDNF-mediated neuroplasticity in preclinical models.

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide that stimulates growth hormone secretion. Considered more potent than GHRP-6 with less appetite stimulation.

Pinealon is a synthetic tripeptide bioregulator (Glu-Asp-Arg) developed in Russia, targeting pineal gland and central nervous system function. Research focuses on sleep regulation, neuroprotection, and cognitive function in aging subjects.

Cortagen is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Pro) developed at the St. Petersburg Institute of Bioregulation and Gerontology. Research focuses on normalizing cerebral cortex function, cognitive enhancement in aging, and neuroprotection.