Research Peptides Directory

Find detailed peptide profiles for Semaglutide, BPC-157, Tirzepatide, and more. Filter by category, development stage, or search by name.

Research Peptide Profiles

Development Stage
Regulatory Approval
Compounding Status

Argireline (Acetyl Hexapeptide-3)

Skin, Hair & Aesthetics

Argireline is a topical anti-wrinkle peptide that may help smooth expression lines by reducing muscle contractions in the face. It's often called 'Botox in a bottle' and is found in many skincare products.

ACTH (Cosyntropin)

Hormones & Endocrine (Non-GH)

ACTH (Cosyntropin) is a diagnostic peptide used in medical settings to test whether your adrenal glands are working properly. It stimulates cortisol production and is primarily a clinical tool, not a performance peptide.

Matrixyl (Palmitoyl Pentapeptide-4)

Skin, Hair & Aesthetics

Matrixyl is a collagen-boosting skincare peptide that may help reduce wrinkles and improve skin firmness. It signals your skin to produce more collagen, the protein that keeps skin looking young.

Thymalin

Immune & Inflammation

Thymalin is an immune peptide derived from the thymus gland that may help restore immune function, especially in older adults. It's been studied for longevity and immune system rejuvenation.

PE-22-28

Cognition, Mood & Neuroprotection

PE-22-28 is a nootropic peptide that may enhance memory and cognitive function by boosting brain-derived growth factors. It's an emerging compound in the cognitive enhancement research space.

FOXO4-DRI

Longevity & Cellular Health

FOXO4-DRI is a peptide designed to selectively remove old, damaged cells (called senescent cells) that build up in the body with age. These cells stop dividing but refuse to die, releasing harmful signals that damage surrounding healthy tissue. FOXO4-DRI works by disrupting a specific protein interaction that keeps these cells alive, allowing them to undergo natural cell death. In animal studies, this led to improved fur growth, kidney function, and overall fitness in aged mice. No human clinical trials have been conducted, and the peptide remains a preclinical research compound.

GHRP-2

Growth Hormone / IGF-1 Axis

GHRP-2 is a growth hormone-releasing peptide similar to GHRP-6 but with less appetite stimulation. It may help improve body composition, recovery, and sleep quality.

Pinealon

Cognition, Mood & Neuroprotection

Pinealon is a short peptide that may support brain function and regulate the sleep-wake cycle by acting on the pineal gland. It's being studied for neuroprotection and age-related cognitive decline.

Cortagen

Cognition, Mood & Neuroprotection

Cortagen is a short peptide that may support brain function and protect against age-related cognitive decline. It's being studied for its effects on brain cell repair and neuroplasticity.

AHK-Cu

Skin, Hair & Aesthetics

AHK-Cu is a copper peptide that may promote hair growth and reduce hair loss by stimulating hair follicle cells. It's being studied as a topical treatment for thinning hair.

About the Directory

How the Research Peptides Directory Works

The PeptideWiki directory organizes research peptides into clear, evidence-based profiles covering mechanisms, dosing, safety, and research status. Browse by category, development stage, or peptide name to compare compounds across weight loss, recovery, growth hormone, cognition, longevity, and more.

Categories

Peptides are grouped by their primary research focus and biological activity, including metabolism, growth hormone signaling, tissue repair, cognition, inflammation, aesthetics, cellular health, sexual health, and endocrine function.

Development Stage

Shows how far a peptide has progressed in the research pipeline. Preclinical compounds are still in laboratory or animal models. Phase 2, 3, and 4 compounds have moved further through human research. Discontinued compounds are no longer being actively developed.

Regulatory Approval

Shows whether a peptide has been cleared by a health authority or is still limited to research. "Not Approved" means no clinical clearance. "Investigational" means still under study. "FDA Approved" means cleared in the United States for specific indications.

Compounding Status

Shows where a peptide sits in the FDA 503A and 503B compounding pathways. Cat 1 compounds are under enforcement discretion and are compoundable today. Cat 2 compounds have safety concerns flagged. Withdrawn, Not Compoundable, and Component of FDA-Approved Drug categories each reflect different regulatory histories.