Research Peptides Directory
Find detailed peptide profiles for Semaglutide, BPC-157, Tirzepatide, and more. Filter by category, development stage, or search by name.
Research Peptide Profiles
Thymosin Alpha-1
Immune & Inflammation
Thymosin Alpha-1 is an immune-boosting peptide that may strengthen your body's defense against infections and support overall immune function. It's approved in several countries for hepatitis treatment.
Cagrilintide
Metabolic & Weight Loss
Cagrilintide is a weekly injection being developed for weight loss. It copies amylin, a hormone your pancreas naturally releases after eating to tell your brain you are full. By boosting that fullness signal and slowing how fast the stomach empties, it helps people eat less without feeling deprived. On its own it produced around 10 percent weight loss in mid-stage studies. Paired with semaglutide in a combination called CagriSema, it reached about 20 percent body-weight loss over roughly 16 months in large late-stage trials, with most side effects being temporary stomach-related issues like nausea. It is made by Novo Nordisk, is still investigational, and is under review by regulators rather than approved for sale.
Gonadorelin (GnRH)
Hormones & Endocrine (Non-GH)
Gonadorelin is a fertility and hormone peptide that triggers the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It's used clinically to test pituitary function and support fertility treatments.
MGF (Mechano Growth Factor)
Performance & Body Composition
MGF (Mechano Growth Factor) is a muscle repair peptide that's released naturally after exercise or injury. It may help speed up muscle recovery and promote new muscle cell growth.
Humanin
Longevity & Cellular Health
Humanin is a naturally occurring mitochondrial peptide that may protect cells from stress and age-related damage. It's being studied for its potential role in Alzheimer's disease, diabetes, and cardiovascular health.
Glutathione
Longevity & Cellular Health
Glutathione is the body's most abundant antioxidant, a small peptide that cells build themselves from three amino acids. It plays a key role in three things: protecting cells from damage by unstable molecules called free radicals, powering the mitochondria that make cellular energy, and helping the liver clear out drugs and toxins. Intracellular levels decline naturally with age, and low levels are linked to chronic illness, fatigue, and slower recovery from stress. People take it as a supplement by mouth (usually in a liposomal liquid for better absorption), through an IV at clinics, sprayed in the nose for brain-related research, or applied topically to the skin. Evidence supports real increases in measurable glutathione levels with supplementation, though the size of clinical effects varies by form, dose, and goal.
GHK (Tripeptide)
Injury, Repair & Recovery
GHK is a naturally occurring copper-binding peptide that may support skin repair, wound healing, and collagen production. It's the base peptide that GHK-Cu is derived from.
GHK-Cu (Copper Peptide)
Skin, Hair & Aesthetics
GHK-Cu is a copper peptide that may improve skin health, promote wound healing, and stimulate collagen production. It's used both as an injection and in topical skincare products.
5-Amino-1MQ
Metabolic & Weight Loss
5-Amino-1MQ is a small molecule that may boost metabolism and promote fat burning by blocking an enzyme called NNMT. It's being studied as a potential treatment for obesity and metabolic disorders.
ARA-290 (Cibinetide)
Immune & Inflammation
ARA-290 is an anti-inflammatory peptide that may help relieve nerve pain and promote tissue repair without suppressing the immune system. It's being studied for diabetic neuropathy and sarcoidosis.
LL-37 (Cathelicidin)
Immune & Inflammation
LL-37 is a natural immune defense peptide that may help fight infections and support the body's ability to ward off bacteria, viruses, and fungi.
HGH Fragment 176-191
Metabolic & Weight Loss
HGH Fragment 176-191 is a fat-burning peptide derived from human growth hormone that targets body fat without the other effects of full HGH. It's essentially the fat-loss portion of growth hormone isolated on its own.
Setmelanotide
Metabolic & Weight Loss
Setmelanotide, sold as Imcivree, is an FDA-approved peptide medicine given as a daily injection under the skin. It works by switching on MC4R, a receptor in the brain that controls the feeling of fullness. The important thing to understand is who it is for: it is approved for people with specific rare conditions (POMC, PCSK1, or LEPR deficiency, Bardet-Biedl syndrome, and acquired hypothalamic obesity) in which the brain's hunger-control pathway is broken or damaged, causing extreme hunger and severe obesity. In those groups, trials showed most patients lost significant weight and felt far less hungry over about a year. It is not approved as a general weight-loss drug, and it has not been shown to work the same way in people whose hunger pathway is normal. The most common and expected side effect is a darkening of the skin and moles, because the receptor it targets also affects skin pigment, along with injection-site reactions and nausea.
Tesofensine
Metabolic & Weight Loss
Tesofensine is an experimental weight-loss pill. It works in the brain by keeping three appetite-related chemicals, noradrenaline, dopamine, and serotonin, active for longer, which strengthens the feeling of fullness and reduces hunger. That is a different approach from the popular injections like semaglutide, which act through a gut hormone. In a 24-week Phase 2 trial of people with obesity, the 0.5 mg dose led to about 9 percent body-weight loss, roughly double what the diet drugs of that era achieved, and the 1.0 mg dose reached about 11 percent. The main drawbacks are a faster heart rate and disturbed sleep, which is why a newer version pairs it with a low dose of a heart-slowing medicine. Tesofensine is taken once a day by mouth, is still investigational, and is not approved for sale.
KPV
Immune & Inflammation
KPV is an anti-inflammatory peptide that may help calm gut inflammation and support digestive health. It's a small fragment of a larger hormone involved in immune regulation.
About the Directory
How the Research Peptides Directory Works
The PeptideWiki directory organizes research peptides into clear, evidence-based profiles covering mechanisms, dosing, safety, and research status. Browse by category, development stage, or peptide name to compare compounds across weight loss, recovery, growth hormone, cognition, longevity, and more.
Categories
Peptides are grouped by their primary research focus and biological activity, including metabolism, growth hormone signaling, tissue repair, cognition, inflammation, aesthetics, cellular health, sexual health, and endocrine function.
Development Stage
Shows how far a peptide has progressed in the research pipeline. Preclinical compounds are still in laboratory or animal models. Phase 2, 3, and 4 compounds have moved further through human research. Discontinued compounds are no longer being actively developed.
Regulatory Approval
Shows whether a peptide has been cleared by a health authority or is still limited to research. "Not Approved" means no clinical clearance. "Investigational" means still under study. "FDA Approved" means cleared in the United States for specific indications.
Compounding Status
Shows where a peptide sits in the FDA 503A and 503B compounding pathways. Cat 1 compounds are under enforcement discretion and are compoundable today. Cat 2 compounds have safety concerns flagged. Withdrawn, Not Compoundable, and Component of FDA-Approved Drug categories each reflect different regulatory histories.